磷脂系列 
壳聚糖-甘露糖，Chitosan-Mannose
chitosan-mannose
| 别称： | Chitosan-Mannose | ||
|---|---|---|---|
| CAS号： | N/A | 产品货号： | THKG01020860 |
| 分子式： | N/A | 溶解性： | |
| 性状： | 白色粉末 | 纯度： | 95% |
| 储存条件： | -20°干燥避光 | 保质期： | 一年 |
*本站全线产品仅供科研使用 |
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壳聚糖-甘露糖，Chitosan-Mannose
chitosan-mannose
| 别称： | Chitosan-Mannose | ||
|---|---|---|---|
| CAS号： | N/A | 产品货号： | THKG01020860 |
| 分子式： | N/A | 溶解性： | |
| 性状： | 白色粉末 | 纯度： | 95% |
| 储存条件： | -20°干燥避光 | 保质期： | 一年 |
*本站全线产品仅供科研使用 |
|||
Chitosan-Mannose conjugate is a strategically engineered glycopolymer that integrates the intrinsic biocompatibility and mucoadhesiveness of chitosan with the specific carbohydrate recognition capabilities of mannose, serving as a multifunctional biological interface for targeted molecular interaction and controlled delivery applications. The conjugate typically exhibits enhanced water solubility compared to native chitosan, particularly in neutral to slightly acidic pH ranges, attributed to the hydrophilic mannose moieties disrupting the intermolecular hydrogen bonding of the chitosan backbone. Its thermal stability profile, with decomposition temperatures ranging from 250-300°C depending on substitution degree, reflects the combined influence of polysaccharide chain integrity and saccharide modification density. In advanced biomedical research, Chitosan-Mannose has emerged as a versatile tool for lectin-mediated targeting, where the mannose residues enable specific binding to C-type lectin receptors (e.g., DC-SIGN) on antigen-presenting cells, facilitating enhanced cellular uptake in vaccine delivery systems. Meanwhile, the chitosan scaffold provides pH-responsive drug release properties through protonation of its glucosamine units under acidic conditions, making it suitable for intracellular cargo delivery applications.
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